NhaX

• Description: general stress protein, putative regulator of nhaC
  
  

Gene name	nhaX
Synonyms	yheK
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: nhaX
MW, pI	17 kDa, 4.438
Gene length, protein length	498 bp, 166 aa
Immediate neighbours	nhaC, yheJ
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU09690

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: universal stress protein A family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O07552

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: nhaX (according to DBTBS)

• Expression browser: nhaX PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • strongly induced in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

Z Prágai, C Eschevins, S Bron, C R Harwood
Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases.
J Bacteriol: 2001, 183(8);2505-15
[PubMed:11274110] [WorldCat.org] [DOI] (P p)