DctR

• Description: two-component response regulator, regulation of the dctS-dctR-dctP operon
  
  

Gene name	dctR
Synonyms	ydbG
Essential	no
Product	two-component response regulator
Function	regulation of the dctS-dctR-dctP operon
Gene expression levels in SubtiExpress: dctR
Interactions involving this protein in SubtInteract: DctR
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism
MW, pI	25 kDa, 8.6
Gene length, protein length	678 bp, 226 aa
Immediate neighbours	dctS, dctP
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

The gene

Basic information

• Locus tag: BSU04460

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by DctS on an Asp residue

• Cofactor(s):

• Effectors of protein activity: phosphorylation likely affects DNA-binding activity

• Interactions:
  • DctS-DctR

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P96602

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dctS-dctR-dctP PubMed

• Expression browser: dctR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Kei Asai, Sang-Hoon Baik, Yasuhiro Kasahara, Shigeki Moriya, Naotake Ogasawara
Regulation of the transport system for C4-dicarboxylic acids in Bacillus subtilis.
Microbiology (Reading): 2000, 146 ( Pt 2);263-271
[PubMed:10708364] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)