NhaK

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  • Description: cation/H+ antiporter

Gene name nhaK
Synonyms yvgP
Essential no
Product cation/H+ antiporter
Function monovalent cation export
Gene expression levels in SubtiExpress: nhaK
MW, pI 75 kDa, 9.222
Gene length, protein length 2010 bp, 670 aa
Immediate neighbours yvgO, cysJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvgP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NhaK expression.png
























Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU33420

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: export of Na(+), K(+), Li(+), Rb(+)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: constitutive, expression increases in the presence of Na(+) and K(+) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Makoto Fujisawa, Ayumi Kusumoto, Yuko Wada, Takahiro Tsuchiya, Masahiro Ito
NhaK, a novel monovalent cation/H+ antiporter of Bacillus subtilis.
Arch Microbiol: 2005, 183(6);411-20
[PubMed:16021482] [WorldCat.org] [DOI] (P p)