SigV

• Description: RNA polymerase ECF-type sigma factor SigV
  
  

Gene name	sigV
Synonyms
Essential	no
Product	RNA polymerase ECF-type sigma factor SigV
Function	response to lysozyme
Gene expression levels in SubtiExpress: sigV
Interactions involving this protein in SubtInteract: SigV
MW, pI	19 kDa, 9.037
Gene length, protein length	498 bp, 166 aa
Immediate neighbours	yrhO, rsiV
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription, sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigV regulon

The SigV regulon:

• sigV-rsiV-oatA-yrhK

The gene

Basic information

• Locus tag: BSU27120

Phenotypes of a mutant

• • increased sensitivity to lysozyme, this can be suppressed by overexpression of oatA PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ECF subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SigV-RsiV
  • SigV-(RpoB-RpoC)

• Localization:

Database entries

• Structure:

• UniProt: O05404

• KEGG entry: [3]

• E.C. number:

Additional information

• Expression of the SigV regulon in increased in ugtP mutants PubMed

Expression and regulation

• Operon: sigV-rsiV-oatA-yrhK PubMed

• Expression browser: sigV PubMed

• Sigma factor: SigV PubMed

• Regulation:
  • induced by lysozyme (SigV) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A907 ( sigV::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Thomas Wiegert, University of Bayreuth, Germany Homepage

References

Additional publications: 21926231,21856855 PubMed