RpsO

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Revision as of 10:56, 26 April 2013 by Jstuelk (talk | contribs) (Expression and regulation)
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Gene name rpsO
Synonyms
Essential yes PubMed
Product ribosomal protein S15 (BS18)
Function translation
Gene expression levels in SubtiExpress: rpsO
Interactions involving this protein in SubtInteract: RpsO
MW, pI 10 kDa, 10.975
Gene length, protein length 267 bp, 89 aa
Immediate neighbours ribC, pnpA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RpsO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RpsO expression.png















Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU16680

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1A32 (Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • translational repression of rpsO expression upon binding of excess RpsO to the untranslated region of the rpsO mRNA PubMed
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is processed, this is initiated by RNase Y and cleavage products are subsequently subject to exonucleolytic degradation by RNases J1 and J2 and by PNPase PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References