ParB

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  • Description: chromosome positioning near the pole and transport through the polar septum / antagonist of Soj-dependent inhibition of sporulation initiation

Gene name spo0J
Synonyms spo0JB
Essential no
Product site-specific DNA-binding protein
Function chromosome positioning before asymmetric septation,

specifying its orientation, and imposing directionality on

its subsequent transport through the septum; required for sporulation

(antagonist of Soj-dependent inhibition of sporulation initiation)

Gene expression levels in SubtiExpress: spo0J

specifying its orientation, and imposing directionality on

its subsequent transport through the septum; required for sporulation

(antagonist of Soj-dependent inhibition of sporulation initiation)

Interactions involving this protein in SubtInteract: Spo0J
MW, pI 32 kDa, 8.417
Gene length, protein length 846 bp, 282 aa
Immediate neighbours yyaC, soj
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Spo0J context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Spo0J expression.png
























Categories containing this gene/protein

DNA condensation/ segregation, sporulation/ other

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU40960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: inhibits Soj dimerization and concomitant DNA-binding activity by stimulating Soj ATPase activity PubMed
  • Protein family: parB family (according to Swiss-Prot)
  • Paralogous protein(s): Noc

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed