HmoA

Gene name	hmoA
Synonyms	yetG
Essential	no
Product	heme monooxygenase
Function	degradation of heme
Gene expression levels in SubtiExpress: hmoA
MW, pI	14 kDa, 9.126
Gene length, protein length	375 bp, 125 aa
Immediate neighbours	yetF, yetH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

acquisition of iron

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU07150

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds hemin in vitro with ~1:1 stoichiometry and degrade hemin in the presence of an electron donor PubMed

• Protein family: antibiotic biosynthesis monooxygenase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31534

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: hmoA (based on genomic context)

• Expression browser: hmoA PubMed

• Sigma factor:

• Regulation:
  • induced by iron limitation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional references: PubMed