SecY

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Gene name secY
Synonyms
Essential yes PubMed
Product preprotein translocase subunit
Function protein secretion
Gene expression levels in SubtiExpress: secY
Interactions involving this protein in SubtInteract: SecY
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 47 kDa, 10.209
Gene length, protein length 1293 bp, 431 aa
Immediate neighbours rplO, adk
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SecY context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

protein secretion, essential genes, membrane proteins, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01360

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: secY/SEC61-alpha family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

universally conserved protein

Expression and regulation

  • Operon: rplO-secY-adk-map
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References