LytC

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  • Description: N-acetylmuramoyl-L-alanine amidase, required for flagellar function PubMed

Gene name lytC
Synonyms cwlB
Essential no
Product N-acetylmuramoyl-L-alanine amidase

(EC 3.5.1.28)

Function major autolysin, cell separation, wall turnover

lysis, motility and general cell lysis induced by sodium azide

MW, pI 52 kDa, 10.108
Gene length, protein length 1488 bp, 496 aa
Immediate neighbours tuaA, lytB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LytC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LytC expression.png
























Categories containing this gene/protein

cell wall degradation/ turnover, motility and chemotaxis

This gene is a member of the following regulons

SigD regulon, SlrR regulon, YvrHb regulon

The gene

Basic information

  • Locus tag: BSU35620

Phenotypes of a mutant

  • impaired in motility, the phenotype is suppressed by mutations in lonA or smiA PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
  • Protein family: N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References