YfkN

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  • Description: extracellular 2',3' cyclic nucleotide phosphodiesterase, 2' (or 3') nucleotidase and 5' nucleotidase

Gene name yfkN
Synonyms
Essential yes PubMed
Product 2',3' cyclic nucleotide phosphodiesterase,
2' (or 3') nucleotidase and 5' nucleotidase
Function probably phosphate acquisition
Interactions involving this protein in SubtInteract: YfkN
MW, pI 159 kDa, 5.021
Gene length, protein length 4386 bp, 1462 aa
Immediate neighbours hypO, yfkM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YfkN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfkN expression.png
























Categories containing this gene/protein

phosphate metabolism, membrane proteins

This gene is a member of the following regulons

CcpA regulon, PhoP regulon

The gene

Basic information

  • Locus tag: BSU07840

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): YhcR

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: extracellular (signal peptide) PubMed, the transmembrane domain serves as retention signal, attached to the cell wall PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed by glucose (5.2-fold) (CcpA) PubMed
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional referencecs: PubMed