RodA

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  • Description: control of cell shape and elongation

Gene name rodA
Synonyms ywcF, ipa-42d
Essential yes PubMed
Product SEDS protein
Function control of cell shape and elongation
MW, pI 43 kDa, 8.759
Gene length, protein length 1179 bp, 393 aa
Immediate neighbours nfrA, ywcE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RodA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell shape, cell envelope stress proteins (controlled by SigM, V, W, X, Y), essential genes, membrane proteins

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU38120

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745] [WorldCat.org] [DOI] (I p)

Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744] [WorldCat.org] [DOI] (I p)

Gonçalo Real, Allison Fay, Avigdor Eldar, Sérgio M Pinto, Adriano O Henriques, Jonathan Dworkin
Determinants for the subcellular localization and function of a nonessential SEDS protein.
J Bacteriol: 2008, 190(1);363-76
[PubMed:17981970] [WorldCat.org] [DOI] (I p)

A O Henriques, P Glaser, P J Piggot, C P Moran
Control of cell shape and elongation by the rodA gene in Bacillus subtilis.
Mol Microbiol: 1998, 28(2);235-47
[PubMed:9622350] [WorldCat.org] [DOI] (P p)