LutR
Revision as of 06:51, 17 April 2012 by 134.76.70.252 (talk)
Gene name | lutR |
Synonyms | yvfI |
Essential | no |
Product | transcriptional repressor, (GntR family) |
Function | control of lactate utilization |
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
MW, pI | 19 kDa, 4.845 |
Gene length, protein length | 525 bp, 175 aa |
Immediate neighbours | lacR, lutP |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The LutR regulon:
The gene
Basic information
- Locus tag: BSU34180
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed
- Protein family: GntR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: lactate acts as molecular inducer PubMed
Database entries
- Structure:
- UniProt: O07007
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Your additional remarks
References
Yunrong Chai, Roberto Kolter, Richard Losick
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
J Bacteriol: 2009, 191(8);2423-30
[PubMed:19201793]
[WorldCat.org]
[DOI]
(I p)
Additional publications: PubMed