YugJ

• Description: similar to NADH-dependent butanol dehydrogenase
  
  

Gene name	yugJ
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	42 kDa, 5.221
Gene length, protein length	1161 bp, 387 aa
Immediate neighbours	yugK, yuzA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

poorly characterized/ putative enzymes

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

• Locus tag: BSU31370

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: iron-containing alcohol dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s): YugK

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O05239

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yugJ PubMed

• Expression browser: yugJ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • Spx: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Original publications

Bauke Oudega, Gregory Koningstein, Luísa Rodrigues, Maria de Sales Ramon, Helmut Hilbert, Andreas Düsterhöft, Thomas M Pohl, Thomas Weitzenegger
Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).
Microbiology (Reading): 1997, 143 ( Pt 8);2769-2774
[PubMed:9274030] [WorldCat.org] [DOI] (P p)

The corresponding protein in E. coli

Changhan Lee, Insook Kim, Junghoon Lee, Kang-Lok Lee, Bumchan Min, Chankyu Park
Transcriptional activation of the aldehyde reductase YqhD by YqhC and its implication in glyoxal metabolism of Escherichia coli K-12.
J Bacteriol: 2010, 192(16);4205-14
[PubMed:20543070] [WorldCat.org] [DOI] (I p)

José Manuel Pérez, Felipe A Arenas, Gonzalo A Pradenas, Juan M Sandoval, Claudio C Vásquez
Escherichia coli YqhD exhibits aldehyde reductase activity and protects from the harmful effect of lipid peroxidation-derived aldehydes.
J Biol Chem: 2008, 283(12);7346-53
[PubMed:18211903] [WorldCat.org] [DOI] (P p)