HxlB

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  • Description: 6-phospho-3-hexuloisomerase

Gene name hxlB
Synonyms yckF
Essential no
Product 6-phospho-3-hexuloisomerase
Function ribulose monophosphate pathway for formaldehyde fixation
MW, pI 19 kDa, 5.791
Gene length, protein length 555 bp, 185 aa
Immediate neighbours tlpC, hxlA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HxlB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HxlB expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

HxlR regulon

The gene

Basic information

  • Locus tag: BSU03450

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate (according to Swiss-Prot)
  • Protein family: PHI subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: induction by formaldehyde (HxlR) PubMed
  • Regulatory mechanism: transcription activation by HxlR PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References