GabR
Revision as of 14:22, 18 April 2012 by 134.76.70.252 (talk)
| Gene name | gabR |
| Synonyms | ycnF |
| Essential | no |
| Product | transcription regulator |
| Function | regulation of gamma-amino butyric acid utilization |
| MW, pI | 54 kDa, 6.709 |
| Gene length, protein length | 1437 bp, 479 aa |
| Immediate neighbours | yczG, gabT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of amino acids, transcription factors and their control
This gene is a member of the following regulons
The GabR regulon:
The gene
Basic information
- Locus tag: BSU03890
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: activity is triggered by gamma-amino butyrate and pyridoxalphosphate PubMed
Database entries
- Structure:
- UniProt: P94426
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- GabR: negative autoregulation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Boris R Belitsky
Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator.
J Mol Biol: 2004, 340(4);655-64
[PubMed:15223311]
[WorldCat.org]
[DOI]
(P p)
Boris R Belitsky, Abraham L Sonenshein
GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis.
Mol Microbiol: 2002, 45(2);569-83
[PubMed:12123465]
[WorldCat.org]
[DOI]
(P p)
