NprB

From SubtiWiki
Revision as of 17:36, 12 April 2012 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: extracellular neutral protease B

Gene name nprB
Synonyms
Essential no
Product extracellular neutral protease B
Function degradation of proteins
MW, pI 59 kDa, 5.322
Gene length, protein length 1614 bp, 538 aa
Immediate neighbours yitR, yitS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NprB context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11100

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Similar, but not identical, to that of thermolysin (according to Swiss-Prot)
  • Protein family: peptidase M4 family (according to Swiss-Prot)
  • Paralogous protein(s): NprE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481] [WorldCat.org] [DOI] (I p)

Original publications