LytG

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  • Description: similar to N-acetylmuramoyl-L-alanine amidase

Gene name lytG
Synonyms yubE
Essential no
Product unknown
Function cell wall turnover
MW, pI 31 kDa, 8.277
Gene length, protein length 846 bp, 282 aa
Immediate neighbours yubF, yubD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YubE context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall degradation/ turnover

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU31120

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolysis of 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid residues in a peptidoglycan (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 73 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Fusinita van den Ent, Mark Leaver, Felipe Bendezu, Jeff Errington, Piet de Boer, Jan Löwe
Dimeric structure of the cell shape protein MreC and its functional implications.
Mol Microbiol: 2006, 62(6);1631-42
[PubMed:17427287] [WorldCat.org] [DOI] (P p)

Gavin J Horsburgh, Abdelmadjid Atrih, Michael P Williamson, Simon J Foster
LytG of Bacillus subtilis is a novel peptidoglycan hydrolase: the major active glucosaminidase.
Biochemistry: 2003, 42(2);257-64
[PubMed:12525152] [WorldCat.org] [DOI] (P p)