QdoI
- Description: Fe-containing quercetin 2,3-dioxygenase
| Gene name | qdoI |
| Synonyms | yxaG |
| Essential | no |
| Product | Fe-containing quercetin 2,3-dioxygenase |
| Function | resistance to plant product quercetin |
| MW, pI | 37,4 kDa, 5.562 |
| Gene length, protein length | 1011 bp, 337 aa |
| Immediate neighbours | yxaH, qdoR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU39980
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: oxidation of the flavonol quercetin with dioxygen, cleaving the central heterocyclic ring and releasing CO
- Protein family:bicupin family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): Mn(II) (preferred), but also active with Fe(II) snd Co(II) PubMed
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 2H0V
- UniProt: P42106
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
J B Broderick
Catechol dioxygenases.
Essays Biochem: 1999, 34;173-89
[PubMed:10730195]
[WorldCat.org]
[DOI]
(P p)
T D Bugg, J Sanvoisin, E L Spence
Exploring the catalytic mechanism of the extradiol catechol dioxygenases.
Biochem Soc Trans: 1997, 25(1);81-5
[PubMed:9056848]
[WorldCat.org]
[DOI]
(P p)
Original publications
