KapB

• Description: activator of KinB, control of the phosphorelay
  
  

Gene name	kapB
Synonyms
Essential	no
Product	activator of KinB in the initiation of sporulation
Function	control of sporulation initiation
Function and regulation of this protein in SubtiPathways: Phosphorelay
MW, pI	14 kDa, 6.816
Gene length, protein length	384 bp, 128 aa
Immediate neighbours	kinB, kapD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU31460

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

phosphorelay, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q08429

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: kinB-kapB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • CodY: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: