SodF

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  • Description: superoxide dismutase

Gene name sodF
Synonyms
Essential no
Product superoxide dismutase
Function detoxification of oxygen radicals
MW, pI 33 kDa, 6.17
Gene length, protein length 843 bp, 281 aa
Immediate neighbours sqhC, yocR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SodF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU19330

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress, membrane proteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 superoxide + 2 H+ = O2 + H2O2 (according to Swiss-Prot)
  • Protein family: terpene cyclase/mutase family (according to Swiss-Prot)
  • Paralogous protein(s): SodA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): contains an iron-sulfur cluster
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during sporulation in the mother cell PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

T Bosak, R M Losick, A Pearson
A polycyclic terpenoid that alleviates oxidative stress.
Proc Natl Acad Sci U S A: 2008, 105(18);6725-9
[PubMed:18436644] [WorldCat.org] [DOI] (I p)