YtrA

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Gene name ytrA
Synonyms
Essential no
Product transcriptional repressor (GntR family)
Function regulation of acetoine uptake
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 14 kDa, 8.094
Gene length, protein length 390 bp, 130 aa
Immediate neighbours ytrB, ytzC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtrA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU30460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 3NEU (similar protein from Listeria innocua, 41% identity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early in the stationary phase PubMed
    • induced by cold shock (5-fold) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Carsten L Beckering, Leif Steil, Michael H W Weber, Uwe Völker, Mohamed A Marahiel
Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis.
J Bacteriol: 2002, 184(22);6395-402
[PubMed:12399512] [WorldCat.org] [DOI] (P p)

K I Yoshida, Y Fujita, S D Ehrlich
An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis.
J Bacteriol: 2000, 182(19);5454-61
[PubMed:10986249] [WorldCat.org] [DOI] (P p)