NrnA

• Description: oligoribonuclease (nanoRNase), 3',5'-bisphosphate nucleotidase
  
  

Gene name	nrnA
Synonyms	ytqI
Essential	no
Product	oligoribonuclease (nanoRNase), 3',5'-bisphosphate nucleotidase
Function	degradation of RNA oligonucleotides,
MW, pI	34 kDa, 4.668
Gene length, protein length	939 bp, 313 aa
Immediate neighbours	ytrI, ytpI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU29250

Phenotypes of a mutant

The mutant requires cysteine PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • Adenosine 3',5'-bisphosphate + H₂O = adenosine 5'-phosphate + phosphate (according to Swiss-Prot)
  • oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase PubMed
  • hydrolyze oligo(deoxy)ribonucleotides in a 5'-3' direction PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• Structure:

• UniProt: O34600

• KEGG entry: [3]

• E.C. number: 3.1.3.7

Expression and regulation

• Operon: nrnA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: