CotH

• Description: spore coat protein (inner)
  
  

Gene name	cotH
Synonyms	ywrH
Essential	no
Product	spore coat protein (inner)
Function	protection of CotU and CotC in the mother cell
MW, pI	42 kDa, 5.953
Gene length, protein length	1086 bp, 362 aa
Immediate neighbours	cotB, cotG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU36060

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cotH family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: spore wall (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q45535

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotH PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, GerE) PubMed

• Regulatory mechanism:
  • GerE: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: