PrpE

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  • Description: protein tyrosine phosphatase

Gene name prpE
Synonyms yjbP
Essential no
Product protein tyrosine phosphatase
Function unknown
MW, pI 27 kDa, 6.747
Gene length, protein length 732 bp, 244 aa
Immediate neighbours yjbO, yjbQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YjbP context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU11630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: P1,P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP (according to Swiss-Prot)
  • Protein family: prpE family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: forespore (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Krzysztof Hinc, Krzysztofa Nagórska, Adam Iwanicki, Grzegorz Wegrzyn, Simone J Séror, Michal Obuchowski
Expression of genes coding for GerA and GerK spore germination receptors is dependent on the protein phosphatase PrpE.
J Bacteriol: 2006, 188(12);4373-83
[PubMed:16740944] [WorldCat.org] [DOI] (P p)

Adam Iwanicki, Anna Herman-Antosiewicz, Marcin Pierechod, Simone J Séror, Michał Obuchowski
PrpE, a PPP protein phosphatase from Bacillus subtilis with unusual substrate specificity.
Biochem J: 2002, 366(Pt 3);929-36
[PubMed:12059787] [WorldCat.org] [DOI] (P p)