Cytochrome P450 family

From SubtiWiki
Revision as of 17:14, 11 August 2010 by Jstuelk (talk | contribs) (Created page with "===The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organ...")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals

B. subtilis encodes eight cytochromes P450:

Relevant reviews

Toshiki Furuya, Daisuke Shibata, Kuniki Kino
Phylogenetic analysis of Bacillus P450 monooxygenases and evaluation of their activity towards steroids.
Steroids: 2009, 74(12);906-12
[PubMed:19559718] [WorldCat.org] [DOI] (I p)

D R Nelson
Cytochrome P450 and the individuality of species.
Arch Biochem Biophys: 1999, 369(1);1-10
[PubMed:10462435] [WorldCat.org] [DOI] (P p)