RapA

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Gene name rapA
Synonyms gsiAA, spo0L
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 44 kDa, 4.848
Gene length, protein length 1134 bp, 378 aa
Immediate neighbours yjoB, phrA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU12430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (4.2-fold) (CcpA) PubMed
    • repressed by casamino acids PubMed
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References