YrkP

• Description: two-component response regulator
  
  

Gene name	yrkP
Synonyms
Essential	no
Product	two-component response regulator
Function	unknown
MW, pI	26 kDa, 5.694
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	yrkQ, yrkO
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU26430

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: OmpR family of two-component response regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by YrkQ on an Asp residue

• Cofactor(s):

• Effectors of protein activity: phosphorylation likely affects DNA-binding activity

• Interactions: YrkQ-YrkP

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P54443

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yrkP-yrkQ-yrkR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YrkP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Taku Ohsawa, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YrkP.
Biosci Biotechnol Biochem: 2008, 72(1);186-96
[PubMed:18175906] [WorldCat.org] [DOI] (I p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)