PyrG

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Revision as of 19:13, 3 February 2010 by Jstuelk (talk | contribs) (Expression and regulation)
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  • Description: CTP synthase (NH3, glutamine)

Gene name pyrG
Synonyms ctrA
Essential yes PubMed
Product CTP synthase (NH3, glutamine)
Function pyrimidine biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Pyrimidines, Nucleotides (regulation)
MW, pI 59 kDa, 5.16
Gene length, protein length 1605 bp, 535 aa
Immediate neighbours ywjG, rpoE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PyrG context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU37150

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + UTP + NH3 = ADP + phosphate + CTP (according to Swiss-Prot)
  • Protein family: CTP synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
    • RNA switch: transcription (termination in the presence of cytidine nucleotides) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References