T-box
The T-box element is an RNA switch that controls genes involved in amino acid metabolism.
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.
Complete list of genes controlled by T-box elements
- Induction by alanine limitation
- Induction by serine limitation
Structure of a T-box ribowsitch
Reviews on T-box regulation
