DhbA

• Description: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
  
  

Gene name	dhbA
Synonyms	entA
Essential	no
Product	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Function	siderophore biosynthesis
MW, pI	27 kDa, 5.311
Gene length, protein length	783 bp, 261 aa
Immediate neighbours	dhbC, besA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU32000

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2,3-dihydro-2,3-dihydroxybenzoate + NAD⁺ = 2,3-dihydroxybenzoate + NADH (according to Swiss-Prot)

• Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P39071

• KEGG entry: [3]

• E.C. number: 1.3.1.28

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • repressed unless the cells enter an iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: