AcuA

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  • Description: protein acetylase for the control of AcsA activity

Gene name acuA
Synonyms
Essential no
Product Gcn5-related N-acetyltransferase
Function control of AcsA activity
MW, pI 24 kDa, 5.028
Gene length, protein length 630 bp, 210 aa
Immediate neighbours acsA, acuB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AcuA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU29690

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: acetylates (and thereby inactivates) AcsA on Lys-549 PubMed PubMed
  • Protein family: acetyltransferase family (according to Swiss-Prot) Gcn5-relatedN-acetyltransferase PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (3.4-fold) (CcpA) PubMed
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References