PpsE

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  • Description: plipastatin synthetase

Gene name ppsE
Synonyms
Essential no
Product plipastatin synthetase
Function production of the antibacterial compound plipastatin
MW, pI 144 kDa, 5.659
Gene length, protein length 3837 bp, 1279 aa
Immediate neighbours yngL, ppsD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PpsE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU18300

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0713 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

K Tsuge, T Ano, M Hirai, Y Nakamura, M Shoda
The genes degQ, pps, and lpa-8 (sfp) are responsible for conversion of Bacillus subtilis 168 to plipastatin production.
Antimicrob Agents Chemother: 1999, 43(9);2183-92
[PubMed:10471562] [WorldCat.org] [DOI] (P p)

Valentina Tosato, Alessandra M Albertini, Michela Zotti, Sabrina Sonda, Carlo V Bruschi
Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168.
Microbiology (Reading): 1997, 143 ( Pt 11);3443-3450
[PubMed:9387222] [WorldCat.org] [DOI] (P p)