TreR

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  • Description: transcription repressor of the treP-treA-treR operon

Gene name treR
Synonyms yfxA
Essential no
Product transcription repressor
Function regulaation of trehalose utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 27 kDa, 6.82
Gene length, protein length 714 bp, 238 aa
Immediate neighbours treA, yfkO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TreR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU07820

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2OGG (effector binding domain)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

L Bürklen, F Schöck, M K Dahl
Molecular analysis of the interaction between the Bacillus subtilis trehalose repressor TreR and the tre operator.
Mol Gen Genet: 1998, 260(1);48-55
[PubMed:9829827] [WorldCat.org] [DOI] (P p)

F Schöck, M K Dahl
Analysis of DNA flanking the treA gene of Bacillus subtilis reveals genes encoding a putative specific enzyme IITre and a potential regulator of the trehalose operon.
Gene: 1996, 175(1-2);59-63
[PubMed:8917076] [WorldCat.org] [DOI] (P p)

F Schöck, M K Dahl
Expression of the tre operon of Bacillus subtilis 168 is regulated by the repressor TreR.
J Bacteriol: 1996, 178(15);4576-81
[PubMed:8755887] [WorldCat.org] [DOI] (P p)