OxdC

• Description: oxalate decarboxylase
  
  

Gene name	oxdC
Synonyms	yvrK
Essential	no
Product	oxalate decarboxylase
Function	unknown
MW, pI	43 kDa, 5.101
Gene length, protein length	1155 bp, 385 aa
Immediate neighbours	yvrJ, yvrL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Oxalate = formate + CO₂ (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s): OxdD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): requires Mn(II) for activity PubMed

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1UW8

• Swiss prot entry: O34714

• KEGG entry: BSU33240

• E.C. number: 4.1.1.2

Expression and regulation

• Operon: oxdC-yvrL PubMed

• Sigma factor: YvrI-YvrH PubMed

• Regulation: induced by acidic growth conditions PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

References

Ellen W Moomaw, Alexander Angerhofer, Patricia Moussatche, Andrew Ozarowski, Inés García-Rubio, Nigel G J Richards
Metal dependence of oxalate decarboxylase activity.
Biochemistry: 2009, 48(26);6116-25
[PubMed:19473032] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J Bacteriol: 2009, 191(3);931-9
[PubMed:19047353] [WorldCat.org] [DOI] (I p)

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed