RsbR

• Description: activator of RsbT kinase activity, part of the stressosome
  
  

Gene name	rsbR
Synonyms	ycxR, rsbRA
Essential	no
Product	activator of RsbT kinase activity
Function	control of SigB activity
MW, pI	30 kDa, 4.731
Gene length, protein length	822 bp, 274 aa
Immediate neighbours	ndoA, rsbS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): RsbRB, RsbRC, RsbRD, YtvA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on Thr-186 PubMed, phosphorylation on Thr-171 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions: RsbR-RsbT, RsbR-RsbS

• Localization:

Database entries

• Structure: 2BNL (N-terminal domain), 3VY9 (complete stressosome)

• Swiss prot entry: P42409

• KEGG entry: BSU04670

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Marles-Wright, J., Grant, T., Delumeau, O., van Duinen, G., Firbank, S. J., Lewis, P. J., Murray, J. W., Newman, J. A., Quin, M. B., Race, P. R., Rohou, A., Tichelaar, W., van Heel, M. & Lewis, R. J. (2008) Molecular architecture of the "stressosome," a signal integration and transduction hub. Science 322: 92-96. PubMed
2. Eymann et al. (2007) Dynamics of protein phosphorylation on Ser/Thr/Tyr in Bacillus subtilis. Proteomics 7: 3509-3526. PubMed
3. Macek et al. (2007) The serine/ threonine/ tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol. Cell. Proteomics 6: 697-707 PubMed
4. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed