MrnC

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  • Description: RNase Mini-III

Gene name mrnC
Synonyms yazC
Essential no
Product RNase Mini-III
Function maturation of 23S rRNA
MW, pI 16 kDa, 9.153
Gene length, protein length 429 bp, 143 aa
Immediate neighbours cysS, yacO
Gene sequence (+200bp) Protein sequence
Genetic context
YazC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RNase III family (but lacks the dsRNA-binding domain)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: RplC binding to the precursor 23S rRNA stimulates MrnC activity PubMed
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

Your additional remarks

References

  1. Redko, Y. & Condon, C. (2009) Ribosomal protein L3 bound to 23S precursor rRNA stimulates its maturation by Mini-III ribonuclease. Mol. Microbiol. 71: 1145-1154. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed