LutR

• Description: transcriptional repressor (GntR family) of the lutA-lutB-lutC operon
  
  

Gene name	lutR
Synonyms	yvfI
Essential	no
Product	transcriptional repressor, (GntR family)
Function	control of lactate utilization
Gene expression levels in SubtiExpress: lutR
Metabolic function and regulation of this protein in SubtiPathways: lutR
MW, pI	19 kDa, 4.845
Gene length, protein length	525 bp, 175 aa
Immediate neighbours	lacR, lutP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

The LutR regulon:

• lutA-lutB-lutC

The gene

Basic information

• Locus tag: BSU34180

Database entries

• BsubCyc: BSU34180

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed

• Protein family: GntR family of transcription factors

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: lactate acts as molecular inducer PubMed

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU34180

• Structure:

• UniProt: O07007

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: lutR PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: TEK1 lutR::Tn10::spc PubMed

• Expression vector: pQE60-lutR (His-tag) PubMed

• lacZ fusion: TEK7 lutR::lacZ::erm PubMed

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Ayten Katatas, Istanbul Technical University, Istanbul, Turkey [3]