SecG

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  • Description: preprotein translocase subunit

Gene name secG
Synonyms yvaL
Essential no
Product preprotein translocase subunit
Function protein secretion
Gene expression levels in SubtiExpress: secG
Interactions involving this protein in SubtInteract: SecG
Metabolic function and regulation of this protein in SubtiPathways:
SecG
MW, pI 7 kDa, 10.413
Gene length, protein length 228 bp, 76 aa
Immediate neighbours yvaK, yvaM
Sequences Protein DNA DNA_with_flanks
Genetic context
SecG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SecG expression.png
























Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU33630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Deletion of secG from the chromosome causes a temperature sensitive secretion defect. PubMed


The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: secG family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jochen Zimmer, Yunsun Nam, Tom A Rapoport
Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature: 2008, 455(7215);936-43
[PubMed:18923516] [WorldCat.org] [DOI] (I p)

Ji-Hyun Shin, Chester W Price
The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.
J Bacteriol: 2007, 189(10);3729-37
[PubMed:17369301] [WorldCat.org] [DOI] (P p)

K H van Wely, J Swaving, C P Broekhuizen, M Rose, W J Quax, A J Driessen
Functional identification of the product of the Bacillus subtilis yvaL gene as a SecG homologue.
J Bacteriol: 1999, 181(6);1786-92
[PubMed:10074070] [WorldCat.org] [DOI] (P p)