AzoR2

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  • Description: similar to NAD(P)H dehydrogenase (quinone)

Gene name azoR2
Synonyms yvaB
Essential no
Product azoreductase
Function resistance to 2-methylhydroquinone
Gene expression levels in SubtiExpress: azoR2
MW, pI 23 kDa, 5.114
Gene length, protein length 633 bp, 211 aa
Immediate neighbours yvaA, yvaC
Sequences Protein DNA DNA_with_flanks
Genetic context
YvaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AzoR2 expression.png
























Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon, SigG regulon

The gene

Basic information

  • Locus tag: BSU33540

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: azoreductase type 1 family (according to Swiss-Prot)
  • Paralogous protein(s): AzoR1

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3P0R (from B. anthracis, 43% identity, 61% similarity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (2-MHQ) (MhqR) PubMed
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 1516 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1290 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References