BesA

• Description: trilactone hydrolase, catalyses ferri-bacillibactin hydrolysis leading to cytosolic iron release
  
  

Gene name	besA
Synonyms	yuiI
Essential	no
Product	trilactone hydrolase
Function	iron acquisition
Gene expression levels in SubtiExpress: besA
Metabolic function and regulation of this protein in SubtiPathways: BesA
MW, pI	35 kDa, 8.203
Gene length, protein length	942 bp, 314 aa
Immediate neighbours	dhbA, yuiH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

acquisition of iron, iron metabolism

This gene is a member of the following regulons

AbrB regulon, Fur regulon, Efp-dependent proteins

The gene

Basic information

• Locus tag: BSU32010

Database entries

• BsubCyc: BSU32010

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU32010

• Structure:

• UniProt: O32102

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: besA PubMed

• Expression browser: besA PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:
  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: