MtnD

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  • Description: 1,2,-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Gene name mtnD
Synonyms ykrZ
Essential no
Product 1,2,-dihydroxy-3-keto-5-methylthiopentene dioxygenase
Function methionine salvage
Gene expression levels in SubtiExpress: mtnD
Metabolic function and regulation of this protein in SubtiPathways:
mtnD
MW, pI 20 kDa, 4.408
Gene length, protein length 534 bp, 178 aa
Immediate neighbours mtnB, ykvA
Sequences Protein DNA DNA_with_flanks
Genetic context
YkrZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MtnD expression.png















Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, most abundant proteins

This gene is a member of the following regulons

S-box

The gene

Basic information

  • Locus tag: BSU13620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO (according to Swiss-Prot)
  • Protein family: acireductone dioxygenase (ARD) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: S-box: transcription termination/ antitermination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed
  • Additional information:
    • belongs to the 100 most abundant proteins PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 4182 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1417 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References