DgkB
- Description: diacylglycerol kinase
| Gene name | dgkB |
| Synonyms | yerQ |
| Essential | yes PubMed |
| Product | diacylglycerol kinase |
| Function | biosynthesis of lipoteichoic acid |
| Gene expression levels in SubtiExpress: dgkB | |
| MW, pI | 33 kDa, 5.635 |
| Gene length, protein length | 909 bp, 303 aa |
| Immediate neighbours | yerP, rlmCD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06720
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU06720
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): BmrU
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU06720
- Structure: 3S40 (from B. anthracis, 32% identity, 68% similarity)
- UniProt: O31502
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- GP1391 dgkB::cat ltaS::aphA3, available in Jörg Stülke's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Stephanie Brown, John P Santa Maria, Suzanne Walker
Wall teichoic acids of gram-positive bacteria.
Annu Rev Microbiol: 2013, 67;313-36
[PubMed:24024634]
[WorldCat.org]
[DOI]
(I p)
Original publications
Satoshi Matsuoka, Michihiro Hashimoto, Yusuke Kamiya, Takeshi Miyazawa, Kazuki Ishikawa, Hiroshi Hara, Kouji Matsumoto
The Bacillus subtilis essential gene dgkB is dispensable in mutants with defective lipoteichoic acid synthesis.
Genes Genet Syst: 2011, 86(6);365-76
[PubMed:22451476]
[WorldCat.org]
[DOI]
(I p)
Agoston Jerga, Ying-Jie Lu, Gustavo E Schujman, Diego de Mendoza, Charles O Rock
Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis.
J Biol Chem: 2007, 282(30);21738-45
[PubMed:17535816]
[WorldCat.org]
[DOI]
(P p)
