SasB

• Description: (p)ppGpp synthetase
  
  

Gene name	sasB
Synonyms	yjbM
Essential	no
Product	(p)ppGpp synthetase
Function	ppGpp synthesis independent from stringent response
Gene expression levels in SubtiExpress: sasB
MW, pI	24 kDa, 6.708
Gene length, protein length	633 bp, 211 aa
Immediate neighbours	yjbL, nadF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

metabolism of signalling nucleotides

The gene

Basic information

• Locus tag: BSU11600

Phenotypes of a mutant

• a relA sasA sasB triple mutant requires branched chain amino acids, methionine and threonine for growth, the requirement can be suppressed by reduced expression of guaB or inactivation of codY PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): SasA

Extended information on the protein

• Kinetic information:

• Domains: single ppGpp synthetase domain PubMed

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31611

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yjbL-sasB-nadF-yjbO PubMed

• Expression browser: yjbM PubMed

• Sigma factor:

• Regulation: expressed during exponential growth

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: