OpuAB

• Description: glycine betaine ABC transporter (permease)
  
  

Gene name	opuAB
Synonyms
Essential	no
Product	glycine betaine ABC transporter (permease)
Function	compatible solute transport
Gene expression levels in SubtiExpress: opuAB
Interactions involving this protein in SubtInteract: OpuAB
Metabolic function and regulation of this protein in SubtiPathways: opuAB
MW, pI	30 kDa, 9.837
Gene length, protein length	846 bp, 282 aa
Immediate neighbours	opuAA, opuAC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, coping with hyper-osmotic stress, membrane proteins

This gene is a member of the following regulons

RemA regulon

The gene

Basic information

• Locus tag: BSU02990

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • uptake of glycine betaine
  • uptake of dimethylglycine PubMed

• Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • OpuAA-OpuAB-OpuAC PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P46921

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: opuAA-opuAB-opuAC PubMed

• Expression browser: opuAB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by osmotic stress PubMed
  • repressed by intracellular glycine betaine PubMed

• Regulatory mechanism:
  • RemA: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage