MinJ

• Description: topological determinant of cell division, part of the Min system (with DivIVA, MinC, MinD), Noc and the Min system ensure the efficient utilization of the division site at midcell in by ensuring Z ring placement
  
  

Gene name	minJ
Synonyms	yvjD, swrAB
Essential	no
Product	topological determinant of cell division
Function	cell division site selection
Gene expression levels in SubtiExpress: minJ
Interactions involving this protein in SubtInteract: MinJ
MW, pI	43 kDa, 9.057
Gene length, protein length	1191 bp, 397 aa
Immediate neighbours	yvkA, swrAA/1
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell division, membrane proteins

The gene

Basic information

• Locus tag: BSU35220

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • (MinC-MinD)-MinJ-DivIVA PubMed, MinJ binds to the N-terminal lipid-binding domain of DivIVA PubMed

• Localization:
  • forms rings at the division septum PubMed
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: O34375

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: swrAA-minJ PubMed

• Expression browser: minJ PubMed

• Sigma factor: SigD PubMed, SigA PubMed

• Regulation:

• Regulatory mechanism:
  • DegU-P: transcription activation (SigA promoter) PubMed
• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Daniel Kearns, Indiana University, Bloomington, USA, homepage

Marc Bramkamp, University of Cologne, Cologne, Germany homepage