YwiE

From SubtiWiki
Revision as of 11:53, 7 January 2014 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: minor cardiolipin synthetase, general stress protein, required for protection against paraquat stress

Gene name ywiE
Synonyms
Essential no
Product minor cardiolipin synthetase
Function phospholipiid biosynthesis, protection against paraquat stress
Gene expression levels in SubtiExpress: ywiE
Metabolic function and regulation of this protein in SubtiPathways:
ywiE
MW, pI 58 kDa, 8.384
Gene length, protein length 1500 bp, 500 aa
Immediate neighbours ywjA, narI
Sequences Protein DNA DNA_with_flanks
Genetic context
YwiE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YwiE expression.png















Categories containing this gene/protein

biosynthesis of lipids, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress, membrane proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU37240

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol (according to Swiss-Prot)
  • Protein family: Cardiolipin synthase subfamily (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alexander Reder, Dirk Höper, Ulf Gerth, Michael Hecker
Contributions of individual σB-dependent general stress genes to oxidative stress resistance of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3601-10
[PubMed:22582280] [WorldCat.org] [DOI] (I p)

Claudia S López, Alejandro F Alice, Horacio Heras, Emilio A Rivas, Carmen Sánchez-Rivas
Role of anionic phospholipids in the adaptation of Bacillus subtilis to high salinity.
Microbiology (Reading): 2006, 152(Pt 3);605-616
[PubMed:16514141] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Fumitaka Kawai, Momoko Shoda, Rie Harashima, Yoshito Sadaie, Hiroshi Hara, Kouji Matsumoto
Cardiolipin domains in Bacillus subtilis marburg membranes.
J Bacteriol: 2004, 186(5);1475-83
[PubMed:14973018] [WorldCat.org] [DOI] (P p)