Rnr

• Description: RNase R, required for protection against paraquat stress
  
  

Gene name	rnr
Synonyms	yvaJ
Essential	no
Product	exoribonuclease RNase R (EC 3.1.-.-)
Function	nonspecific degradation of rRNA
Gene expression levels in SubtiExpress: rnr
MW, pI	88 kDa, 5.703
Gene length, protein length	2337 bp, 779 aa
Immediate neighbours	smpB, yvaK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, Rnases, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU33610

Database entries

• BsubCyc: BSU33610

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 3'-5'-exoribonuclease

• Protein family: ribonuclease II (RNB) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU33610

• Structure:

• UniProt: O32231

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:
  • secG-yvaK-rnr-smpB-ssrA PubMed
  • yvaK-rnr-smpB-ssrA PubMed

• Expression browser: rnr PubMed

• Sigma factor:
  • yvaK: SigB PubMed

• Regulation:
  • yvaK: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage