OxdD

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  • Description: oxalate decarboxylase, inner spore coat protein

Gene name oxdD
Synonyms yoaN
Essential no
Product oxalate decarboxylase
Function protection of the spore
Gene expression levels in SubtiExpress: oxdD
MW, pI 43 kDa, 5.359
Gene length, protein length 1176 bp, 392 aa
Immediate neighbours yozS, yoaO
Sequences Protein DNA DNA_with_flanks
Genetic context
YoaN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
OxdD expression.png















Categories containing this gene/protein

sporulation proteins, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

SigK regulon, GerE regulon

The gene

Basic information

  • Locus tag: BSU18670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Oxalate = formate + CO2 (according to Swiss-Prot)
  • Protein family: UPF0361 family (according to Swiss-Prot)
  • Paralogous protein(s): OxdC

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Miia R Mäkelä, Kristiina Hildén, Taina K Lundell
Oxalate decarboxylase: biotechnological update and prevalence of the enzyme in filamentous fungi.
Appl Microbiol Biotechnol: 2010, 87(3);801-14
[PubMed:20464388] [WorldCat.org] [DOI] (I p)

Original publications

Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814] [WorldCat.org] [DOI] (I p)

Sébastien Potot, Cláudia R Serra, Adriano O Henriques, Ghislain Schyns
Display of recombinant proteins on Bacillus subtilis spores, using a coat-associated enzyme as the carrier.
Appl Environ Microbiol: 2010, 76(17);5926-33
[PubMed:20601499] [WorldCat.org] [DOI] (I p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Teresa Costa, Leif Steil, Lígia O Martins, Uwe Völker, Adriano O Henriques
Assembly of an oxalate decarboxylase produced under sigmaK control into the Bacillus subtilis spore coat.
J Bacteriol: 2004, 186(5);1462-74
[PubMed:14973022] [WorldCat.org] [DOI] (P p)

A Tanner, L Bowater, S A Fairhurst, S Bornemann
Oxalate decarboxylase requires manganese and dioxygen for activity. Overexpression and characterization of Bacillus subtilis YvrK and YoaN.
J Biol Chem: 2001, 276(47);43627-34
[PubMed:11546787] [WorldCat.org] [DOI] (P p)