PbpX

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  • Description: penicillin-binding protein X

Gene name pbpX
Synonyms
Essential no
Product penicillin-binding protein X
Function endopeptidase
Gene expression levels in SubtiExpress: pbpX
MW, pI 43 kDa, 9.711
Gene length, protein length 1173 bp, 391 aa
Immediate neighbours recA, rny
Sequences Protein DNA DNA_with_flanks
Genetic context
PbpX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PbpX expression.png















Categories containing this gene/protein

cell wall synthesis, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigM regulon, SigX regulon

The gene

Basic information

  • Locus tag: BSU16950

Phenotypes of a mutant

  • increased sensitivity to lysozyme PubMed
  • inactivation of pbpX strongly restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed