YhdK

• Description: anti-SigM protein
  
  

Gene name	yhdK
Synonyms
Essential	no
Product	anti-SigM protein
Function	control of SigM activity
Gene expression levels in SubtiExpress: yhdK
Interactions involving this protein in SubtInteract: YhdK
MW, pI	10 kDa, 8.134
Gene length, protein length	288 bp, 96 aa
Immediate neighbours	yhdJ, yhdL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

• Locus tag: BSU09500

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SigM-YhdK-YhdL PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O07580

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sigM-yhdL-yhdK PubMed

• Expression browser: yhdK PubMed

• Sigma factor: SigA PubMed, SigM PubMed

• Regulation:
  • induced by paraquat (SigM) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • BP97 (D(sigM-yhdL-yhdK)::aphA3), available in Fabian Commichau's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421] [WorldCat.org] [DOI] (P p)

Mika Yoshimura, Kei Asai, Yoshito Sadaie, Hirofumi Yoshikawa
Interaction of Bacillus subtilis extracytoplasmic function (ECF) sigma factors with the N-terminal regions of their potential anti-sigma factors.
Microbiology (Reading): 2004, 150(Pt 3);591-599
[PubMed:14993308] [WorldCat.org] [DOI] (P p)

S Ishikawa, Y Hara, R Ohnishi, J Sekiguchi
Regulation of a new cell wall hydrolase gene, cwlF, which affects cell separation in Bacillus subtilis.
J Bacteriol: 1998, 180(9);2549-55
[PubMed:9573210] [WorldCat.org] [DOI] (P p)